Contact, Imaging & BioInformatics
- Laura Bertens
- LIACS, Leiden University
- Niels Bohrweg 1
- 2333 CA Leiden
- The Netherlands
- Office 115, Snellius Building
- Phone +31 - (0)71 - 527 5791
- Fax +31 - (0)71 527 6985
- Email lbertens@liacs.nl
- URL Bio-Imaging Group
Notes
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Pages last edited February 2010.
Research Areas
3D and 4D modelling and analysis of organ systems in vertebrate development. Work is being done on heart development in Testudines (Emys orbicularis), AP-axis formation in Xenopus laevis, brain development in zebrafish and bile ducts in the human liver. All projects serve a double purpose: on the one hand answering biological questions and gaining knowledge about biological structures by means of visualising those in 3D reconstructions, on the other hand optimizing the software that is currently being used for visualisation, TDR-3Dbase, and developing new software tools for analysis of the models.
Student projects
- Assistent for Human Computer Interaction (Fons Verbeek, 2007-2008)
- Assistant for
Microscopy, Modelling and visualisation, i.e. Image Analysis in Microscopy (Fons Verbeek and Nies Huijsmans, 2008)
- Member of operations team for CHI-NL conference 2009
- Lecturer for Master course Biomodeling and Petri Nets 2009-2010.
Publications
Bertens, L.M.F., Richardson M.K., Verbeek, F.J. (2010) “Analysis of cardiac development in the turtle Emys orbicularis (Testudines; Emidydae) using 3D computer modelling from histological sections”. Anatomical Record (in press).
Yan K., Bertens L.F.M., Verbeek F.J. (2010) “Image registraton and realignment using evolutionary algorithms with high resolution 3D model from human liver”. Proceedings CGIM 2010 11th IASTED Int. Conf. Computer Graphics and Imaging . Innsbruck, Austria, February 2010. (in press).
Brittijn S.A., Duivesteijn S.J., Belmamoune M., Bertens L.M.F., Bitter W., de Bruijn J., Champagne D.L., Cuppen E., Flik G., Vandenbroucke-Grauls C.M., Janssen R.A.J., de Jong I.M.L., de Kloet E.D., Kros A., Meijer A.H., Metz J.R., van der Sar A.M., Schaaf M.J.M., Schulte-Merker S., Spaink H.P., Tak P.P., Verbeek F.J., Vervoordeldonk M.J., Vonk F.J., Witte F., Yuan H., Richardson M.K. (2009) "Zebrafish development and regeneration: new tools for biomedical research”. International Journal of Developmental Biololgy 53: 835-850.
Belmamoune, M., Bertens, L.M.F., Van der Velde, R., Verbeek, F.J. (2008), “The 3D digital atlas of zebrafish: 3D models vizualisation through the internet” (in press).
V an der Putten P., Bertens L.M.F., Liu J., Hagen F., Boekhout T., Verbeek F.J. (2007), “Classification of Yeast Cells from Image Features to Evaluate Pathogen Conditions”, Proc. SPIE Vol. 6506, MultiMedia Content Access: Algorithms & Systems , Vol. 6506 (Eds Hanjalic, A., Schettini, R., Sebe, N.), 65060I-1,65060I-14.