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Contact, Imaging & BioInformatics

Laura Bertens
LIACS, Leiden University
Niels Bohrweg 1
2333 CA Leiden
The Netherlands
Office 115, Snellius Building
Phone +31 - (0)71 - 527 5791
Fax +31 - (0)71 527 6985
Email lbertens@liacs.nl
URL Bio-Imaging Group

Notes

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Pages last edited March 2011.

 

Research Interests

Modelling of vertebrate development, using various techniques. Work is being done on 1) 3D visualisation of heart development in the turtle species Emys orbicularis, 2) process modelling and analysis, using Petri nets, of the AP-axis formation in the frog Xenopus laevis and 3) building a dynamic ontology of the anatomy, physiology and development of the vertebrate heart.

Conferences

Integrative Bioinformatics 2011 Wageningen, 21-23 march, short paper and presentation 'A cross-species vertebrate heart ontology including 3D visualisation', with Joris Slob

Lorentz Workshop 2010, 'Modeling with images in the life sciences', 29 nov - 3 dec, poster 'A dynamic ontology of the heart', with Joris Slob

Petri Nets 2010 Braga, 20-25 june, full paper and presentation 'Modelling Gradients Using Petri Nets', with J Kleijn, M. Koutny and F. Verbeek

Petri Nets 2009 Paris, 22-26 june, attended

CHI Nederland Conferentie 2009, member of organisation

14th Benelux Congress of Zoology, 1-2 nov 2007, presentation '3D Computer visualisation of cardiac development in the turtle Emys orbicularis'

Education

feb-may 2011 Biomodeling and Petri nets; lecturer, together with Jetty Kleijn

sept-dec 2010 Human Computer Interaction; assistant for Fons Verbeek

sept-dec 2009 Biomodeling and Petri nets; lecturer, together with Jetty Kleijn

feb-may 2008 Microscopy, Modelling and Visualisation; assistant for Fons Verbeek

sept-dec 2007 Human Computer Interaction; assistant for Fons Verbeek

 

Informal Presentations

19-10-2010 group meeting LIACS, 'Heart anatomy ontology', with Joris Slob

08-06-2010 This week's discovery: ‘Cardiac development in the turtle Emys orbicularis using 3D computer modelling'

05-03-2010 research presentation for School of Computing Science, Newcastle 'Petri nets and AP axis formation in Xenopus laevis'

09-11-2009 weekly meeting Cell Observatory: 'Petri nets and AP axis formation in Xenopus laevis'

28-04-2009 group meeting LIACS 'Petri nets and AP axis formation in Xenopus laevis'

 

Publications

2010

  • Bertens, L.M.F. , Richardson, M.K. & Verbeek, F.J. (2010).
    Analysis of cardiac development in the turtle Emys orbicularis (Testudines: Emidydae) using 3D computer modeling and reconstruction based on serial sections. Anatomical Record , 293, pp. 1101-1114.
  • Yan, K. , Bertens, L.M.F. & Verbeek, F.J. (2010).
    Image Registraton and Realignment using Evolutionary Algorithms with High resolution 3D model from Human Liver. In A.D. Sappa (Ed.), Proceedings 11th IASTED International Conference on Computer Graphics and Imaging (CGIM 2010)}, (pp. track 679-014
  • Bertens, L.M.F. , Kleijn, J. , Koutny, M. & Verbeek, F.J. (2010).
    Modelling Gradients Using Petri Nets. Proceedings International Workshop on Biological Processes & Petri Nets (BioPPN) Braga, Portugal, June 21 2010 (pp. 55-69)

2009

  • Brittijn, S.A. , Duivesteijn, S.J. , Belmamoune, M. , Bertens, L.M.F. , Bitter, W. , de Bruijn, J. D. , Champagne, D. L. , Cuppen, E. , Flik, G. , Van den Broucke-Grauls, C. M. , Janssen, R. , de Jong, I. E. M. , De Kloet, E. R. , Kros, A. , Meijer, A. , Metz, J. R. , van der Sar, A. M. , Schaaf, M. J. , Schulte-Merker, S. , Spaink, H. P. , Tak, P. P. , Verbeek, F.J. , Vervoordeldonk, M.J. , Vonk, F. , Witte, F. , Yuan, H. & Richardson, M.K. (2009).
    Zebrafish development and regeneration: new tools for biomedical research. International Journal of Developmental Biology , 53 (5-6), pp. 835-850.
  • Bertens, L.M.F. , Jansen, H.J. , Kleijn, J. , Koutny, M. & Verbeek, F.J. (2009).
    Using Petri Nets in Higher Level Development Biology: A case study on the AP axis development in Xenopus laevis. Extended abstract . onbekend: LIACS.

2008

  • Richardson, M.K. , Bertens, L.M.F. , Belmamoune, M. & Verbeek, F.J. (2008).
    Zebrafish Developmental Patterning: New Tools for Medical Research. International Journal of Developmental Biology

2007

  • Putten, P.W.H. van der , Bertens, L.M.F. , Liu, J. , Hagen, F , Boekhout, T. & Verbeek, F.J. (2007).
    Classification of Yeast Cells from Image Features to Evaluate Pathogen Conditions. In Hanjalic, A., Schettini, R., Sebe, N. (Ed.), SPIE Vol. 6506: Vol. 6506. (pp. 650601-14)
 

 

 

2005 Fons J. Verbeek (c)